Antimalarial Activity of Khaya Grandifoliola Stem-bark
نویسندگان
چکیده
منابع مشابه
Antimalarial and Reno-protective Potentials of Combined Stem Bark Extracts of Khaya grandifoliola and Enantia chlorantha in Plasmodium Infected Mice
Background: Malaria is a worldwide threat, which affects millions of people. Although several antimalarial has been reported, they are either not effective or toxic. This study evaluated the antimalarial efficacy and safety of stem bark aqueous extracts of Khaya grandifoliola (KG) and Enantia chlorantha (EC) in Plasmodium berghie (NK65S) infected Swiss mice. Methods: Forty-two animals were gro...
متن کاملChemotherapeutic interaction between Khaya grandifoliola (WELW) CDC stem bark extract and two anti-malarial drugs in mice.
In malarial endemic countries especially in the tropics, conventional antimalarial drugs are used with herbal remedies either concurrently or successively. Khaya grandifoliola is one of such popular herbs used in the treatment of malaria.Various doses of ethanol extract of K. grandifoliola stem bark (50-400 mg/kg/day) were administered orally to Swiss albino mice infected with Plasmodium yoelii...
متن کاملEffects of Aqueous Bark Extracts of Khaya grandifoliola and Enantia chlorantha on Some Biochemical Parameters in Swiss Mice
Background: In this study, the potential side effects of Khaya grandifolola (KG) and Enatia chlorantha (EC) were investigated on liver function and hematological parameters of Swiss albino mice infected with malaria. Method: This study was carried out in part in the Department of Biochemistry, Kwara State University, Malete, and in part in the Department of Biochemistry, Faculty of Life Scienc...
متن کاملEffects of Aqueous Bark Extracts of Khaya grandifoliola and Enantia chlorantha on Some Biochemical Parameters in Swiss Mice
Background: In this study, the potential side effects of Khaya grandifolola (KG) and Enatia chlorantha (EC) were investigated on liver function and hematological parameters of Swiss albino mice infected with malaria. Method: This study was carried out in part in the Department of Biochemistry, Kwara State University, Malete, and in part in the Department of Biochemistry, Faculty of Life Science...
متن کاملActive chemical fractions of stem bark extract of Khaya grandifoliola C.DC and Entada africana Guill. et Perr. synergistically protect primary rat hepatocytes against paracetamol-induced damage
BACKGROUND Khaya grandifoliola (Meliaceae) and Entada africana (Fabaceae) are traditionally used in Bamun (a western tribe of Cameroon) traditional medicine for the treatment of liver related diseases. In this study, the synergistic hepatoprotective effect of respective active fractions of the plants were investigated against paracetamol-induced toxicity in primary cultures of rat hepatocytes. ...
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ژورنال
عنوان ژورنال: Pharmaceutical Biology
سال: 1998
ISSN: 1388-0209,1744-5116
DOI: 10.1076/phbi.36.1.8.4613